Direct oral anticoagulants, vitamin K antagonists, and simple single tooth extraction
نویسندگان
چکیده
منابع مشابه
Vitamin K antagonists, direct oral anticoagulants, and the rationale for reversal agents.
Despite these advantages, clinicians have been concerned over the lack of specific reversal agents for use in the event of a life-threatening bleeding event or when an emergent interventional procedure is required. This concern may limit the use of DOACs, as warfarin can be reversed with the combination of a factor product (fresh frozen plasma or prothrombin complex concentrate) and phytonadion...
متن کامل[Established anticoagulants in secondary haemostasis--Vitamin K antagonists, heparins].
In respect to the actual discussion of new anticoagulants in secondary haemostasis, we will give a short review on established oral anticoagulation with vitamin K antagonists and parenteral anticoagulation by use of heparin. The different coumarin derivatives phenprocoumon, warfarin, and acenocoumarol are compared concerning to the management and influence of pharmacogenetic and pharmacokinetic...
متن کاملIs it necessary to alter anticoagulation therapy for tooth extraction in patients taking direct oral anticoagulants?
BACKGROUND The number of patients using direct oral anticoagulants (DOACs) instead of vitamin K antagonists (VKA) is increasing and there is limited data on the safety of tooth extractions in patients taking DOACs. The aim of this study was to compare the amount of bleeding (AOB) and postoperative complications after tooth extractions between patients taking VKAs and patients taking DOACs witho...
متن کاملNon-Vitamin K Oral Anticoagulants in Stroke Patients: Practical Issues
Significance of imaging The concept of “1-3-6-12 day rule” was recently mentioned as a consensus approach for recommendations for anticoagulation in patients with cerebral ischemic event, either transient ischemic attack or stroke. As mentioned by the authors, the initiation of anticoagulation in these patients depends on various factors. However, the decision to initiate or restart the anticoa...
متن کاملLaboratory monitoring of the non-vitamin K oral anticoagulants.
A lthough they are valuable when used to reduce the risk of thrombosis in several diverse clinical conditions, the vitamin K antagonists (VKAs) bring with them several challenges. These include the need for regular blood tests (perhaps 4 to 6 times weekly), which are expensive and inconvenient to manage; a narrow therapeutic window; interactions with many other drugs; alcohol and diet restricti...
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ژورنال
عنوان ژورنال: Clinical Oral Investigations
سال: 2019
ISSN: 1432-6981,1436-3771
DOI: 10.1007/s00784-019-02836-w